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Differentiation between free and bound leptin in depressed patients
Authors:Maria Strauss,Roland Mergl,Juergen Kratzsch,Mathias Brü  gel,Erik Strauss,Ulrich Hegerl,Peter Schoenknecht
Affiliation:1. Department of Psychiatry and Psychotherapy, University of Leipzig, Semmelweisstraße 10, 04103 Leipzig, Germany;2. Institute of Laboratory Medicine, Clinical Chemistry and Molecular Diagnostics, University of Leipzig, Germany;3. Institute of Clinical Chemistry, Ludwig-Maximilians-University Munich, Germany;4. Medical Practice for Neurology, Psychiatry and Psychotherapy, Kopfzentrum Leipzig®, Germany
Abstract:The relationship between leptin and affective disorders is still unknown. We measured free and bound leptin in 13 drug naïve subjects. Leptin did not significantly differ between patients and controls. As part of future studies, it also appears useful to distinguish between free and bound leptin.
Keywords:Soluble leptin receptor   Affective disorders   Cerebrospinal fluid
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