Dynamics of interleukin-21 production during the clinical course of primary and secondary dengue virus infections |
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Authors: | H. Vivanco-Cid,M.J. Maldonado-Renterí a,L.A. Sá nchez-Vargas,I.Y. Izaguirre-Herná ndez,K.G. Herná ndez-Flores,R. Remes-Ruiz |
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Affiliation: | 1. Instituto de Investigaciones Medico-Biológicas, Universidad Veracruzana, Veracruz, México;2. Hospital Regional de Alta Especialidad de Veracruz, Servicios de Salud de Veracruz, México;3. Universidad del Valle de México, campus Villa Rica, Facultad de Medicina “Dr. Porfirio Sosa Zárate”, México |
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Abstract: | Previous studies have revealed the clinical relevance of pro-inflammatory cytokine production during dengue virus (DENV) infections. In this study, we evaluated the production of interleukin-21 (IL-21), a key soluble mediator mainly produced by CD4+ T cells. |
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Keywords: | Dengue Interleukin 21 Antibody response Cellular immunity |
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