脑内原发性淋巴瘤的MRI诊断

目的:探讨脑内原发性淋巴瘤的MRI特征,以提高认识和诊断水平。方法:回顾性分析8例经手术病理证实的脑内原发淋巴瘤患者的MRI表现。结果:脑内淋巴瘤MRI表现为:①肿瘤单发或多发,以幕上分布为主;②形态圆形或不规则形,T1WI呈低信号,T2WI以高信号为主,信号不均匀;③瘤周水肿及占位效应较轻;④增强扫描肿瘤明显不均匀强化;⑤可侵及软脑膜、室管膜并沿之播散;⑥肿瘤对放疗和化疗敏感;形态、大小变化明显。结论:尽管脑内原发性淋巴瘤缺乏特征性的影像学表现,但全面分析其MRI表现,能够明显提高本病的诊断率。

MRI diagnosis of primary malignant lymphomas in the brain

Objective: To investigate the MRI features of primary lymphoma in the brain for the purpose of improvement of the understanding and diagnostic level.Methods: MRI features from 8 cases of primary malignant lymphoma in the brain confirmed surgically and pathologically were analyzed retrospectively.Results: MRI features of primary malignant lymphoma were as follows: ①single or multiple lesions,mostly in supratentorial region;②round or irregular in shape,hypointense on T1WI,hypointense or isointense on T2WI with homogenous signal;③mild edema around the lesion with mild space occupying effect;④remarkable enhancement of the lesion;⑤involvement of leptomeninges and/or dissemination via ventricular ependyma;⑥sensitive to chemotherapy and radiotherapy.Size and shape changed remarkedly after treatment.Conclusion: Although there are no characteristic imaging findings in primary malignant lymphoma in the brain,the diagnostic accuracy could be highly improved after overall analysis of the MRI appearances.