胸腹腔镜治疗食管癌的临床疗效及对患者血清C反应蛋白与凝血功能的影响

目的 分析胸腹腔镜治疗食管癌的临床疗效及对患者血清C反应蛋白(CRP)与凝血功能的影响.方法选取84例食管癌患者,参照抽签法分作对照组和研究组,每组各42例,对照组行传统开放手术治疗,研究组行胸腹腔镜手术治疗,对比两组患者的手术情况、临床疗效、血清CRP水平及凝血功能.结果研究组手术时间、术中失血量、排气时间均优于对照组(P<0.05),两组患者淋巴结清扫总数、凝血功能及临床疗效比较,差异无统计学意义(P>0.05);术后,研究组患者血清CRP水平明显低于对照组(P<0.01).结论胸腹腔镜治疗食管癌的临床疗效值得肯定,术后血清CRP水平相对较低,但对凝血功能有一定的影响,临床上应加强监测.

The clinical curative effect of combined thoracoscopic and laparoscopic surgery for esophageal cancer and the effect on serum C-reactive protein and coagulation

Objective To analyze the clinical curative effect of combined thoracoscopic and laparoscopic surgery in the treatment of esophageal cancer, and evaluate the influence of combined therapy on serum C-reactive protein (CRP) and coagulation in esophageal cancer patients. Method 84 cases of esophageal cancer patients were included in the anal-ysis, and were randomized as control group and study group, with 42 cases in each, for which the traditional open surgery or combined thoracoscopic and laparoscopic surgery were administered, respectively, and the surgery measures, clinical cura-tive effect, serum CRP level, and coagulation of those patients were compared. Result The operative time, intra-operative blood loss and first time to flatus were better in study group than that of control group (P<0.05), the total number of re-sected lymph nodes, coagulation and clinical curative effect in the two groups were of no significant difference (P>0.05);After surgery, the serum CRP level was significantly decreased and lower in study group than that of the control group (P<0.01). Conclusion The curative effect of combined thoracoscopic and laparoscopic surgery is of affirmative efficacy in the treatment of esophageal cancer, with lower postoperative serum CRP level and limited impact on coagulation, which should be monitored in clinical practice.