绝经过渡期妇女卵巢体积及动脉血流量改变对性激素和脂代谢的影响

目的 探讨绝经过渡期妇女卵巢体积及动脉血流量改变对性激素和脂代谢的影响.方法 选择绝经过渡期妇女106例纳入观察组,同时选择行月经正常妇女98例纳入对照组.比较2组卵巢体积及血流动力学指标,性激素、血脂水平并对卵巢体积及血流动力学与性激素、血脂指标进行相关性分析.结果 观察组卵巢体积明显小于对照组,RI较对照组明显增加,PI则明显降低（P＜0.05）.观察组FSH、LH明显低于对照组,E2、P则明显高于对照组,差异有统计学意义（P＜0.05）.观察组FSH、LH、E2、P均明显高于对照组,差异有统计学意义（P＜0.05）.观察组血清TC、TG、HDL、LDL均明显高于对照组,差异有统计学意义（P＜0.05）.RI与FSH、LH、E2及P呈正相关（P＜0.05）.PI与FSH、LH、E2及P负相关（P＜0.05）.RI与TC、LDL呈正相关（P＜0.05）.PI与TC、LDL呈负相关（P＜0.05）.结论 绝经过渡期妇女卵巢体积缩小、动脉血流动力学已发生较明显改变,同时伴有卵巢功能下降,性激素水平不稳定、血脂水平等改变,进而加速了绝经过渡期妇女卵巢衰退.

Influence of Ovarian Volume and Arterial Blood Flow on Sex Hormone and Lipid Metabolism in Perimenopausal Women

Objective To explore the influence of ovarian volume and arterial blood flow on sex hormone and lipid metabolism in perimenopausal women.Methods 106 cases of perimenopausal women were selected into observation group,and 98 women who were done physical examination at the same time with normal menstruation,they were selected into control group.the ovarian volume and hemodynamic indexes,sex hormone,blood lipid levels between two groups were compared,the correlation of between ovarian volume,hemodynamics and sex hormone,blood lipid were analyzed.Results The ovarian volume of observation group was significantly smaller than that of control group,the RI of observation group increased significantly compared with control group,the PI of observation group decreased significantly （P＜0.05）.the FSH,LH,E2,P of observation group were significantly higher than those of control group,the differences were statistically significant （P＜0.05）.the TC,LDL of observation were significantly higher than those of control group,the difference were statistically significant （P＜0.05）.RI were positively correlated with FSH,LH,E2 and P （P＜0.05）.PI were negativly correlated with FSH,LH,E2 and P （P＜0.05）.RI were positively correlated with TC,LDL （P＜0.05）.PI were negatively correlated with TC,LDL （P＜0.05）.Conclusions The ovarian volume has lessened and arterial hemodynamics has obvious changes in perimenopausal women,at the same time,those accompany with ovarian function decreasing,sex hormone destabilizing,blood lipid level changes,so that the ovarian of perimenopausal women has been accelerated to decline.