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云南鼓槌石斛提取物体外自由基清除活性研究
引用本文:文小玲,王娅娟,徐俊驹,张君,张凯丽,李玉鹏. 云南鼓槌石斛提取物体外自由基清除活性研究[J]. 昆明医学院学报, 2014, 35(12): 4-6
作者姓名:文小玲  王娅娟  徐俊驹  张君  张凯丽  李玉鹏
作者单位:1. 昆明医科大学人事处,云南昆明 650500;昆明医科大学药学院暨云南省天然药物药理重点实验室,云南昆明 650500
2. 昆明医科大学药学院暨云南省天然药物药理重点实验室,云南昆明,650500
3. 云南农业大学烟草学院,云南昆明,650201
基金项目:国家自然科学基金资助项目,云南省应用基础研究基金资助项目
摘    要:目的 研究鼓槌石斛(Dendrobium chrysotoxum) 95%乙醇、石油醚、乙酸乙酯、正丁醇、甲醇五种粗提物体外自由基清除活性.方法 采用DPPH自由基清除法对云南鼓槌石斛五种提取物的体外自由基清除作用进行研究.结果 鼓槌石斛乙酸乙酯粗提物的自由基清除效果最显著,其IC50为0.12 mg/mL.结论 鼓槌石斛提取物在体外自由基清除活性方面有一定的应用价值.

关 键 词:鼓槌石斛  药用植物  自由基清除活性

In Vitro Radical Scavenging Activity of Extracts from Dendrobium chrysotoxum in Yunnan
WEN Xiao-ling,WANG Ya-juan,XU Jun-ju,ZHANG Jun,ZHANG Kai-li,LI Yu-peng. In Vitro Radical Scavenging Activity of Extracts from Dendrobium chrysotoxum in Yunnan[J]. Journal of Kunming Medical College, 2014, 35(12): 4-6
Authors:WEN Xiao-ling  WANG Ya-juan  XU Jun-ju  ZHANG Jun  ZHANG Kai-li  LI Yu-peng
Affiliation:WEN Xiao-ling,WANG Ya-juan,XU Jun-ju,ZHANG Jun,ZHANG Kai-li,LI Yu-peng (1 Dept. of Personnel; 2 School of Pharmaceutical Science & Yunnan Key Laboratory of Pharmacology for Natural Products, Kunming Medical University, Ktmming Yunnan 650500; 3 College of Tobacco Science, Yunnan Agricultural University, Kunming Yunnan 650201, China)
Abstract:Objective To investigate the in vitro radical scavenging activity of extracts from Dendrobium chrysotoxum,including 95% ethanol,petroleum ether,ethyl acetate,n-butanol and methanol extracts.Methods DPPH radical scavenging activity method was used to research the in vitro activity of five crude extracts.Results The results showed that the ethyl acetate extract exhibited a good scavenging action (IC50 =0.12 mg/mL).Conclusion The extracts from D.chrysotoxum have a certain value in antioxidant aspect.
Keywords:Dendrobium chrysotoxum  Medicinal plant  Radical scavenging activity
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