降尿酸对老年高血压合并糖尿病的高尿酸患者血糖的影响

目的 研究老年高血压合并糖尿病的高尿酸血症患者中降低高尿酸水平对血糖的影响.方法 老年高血压合并糖尿病的高尿酸血症患者100例,分为对照组和干预组.对照组给予常规的饮食控制、降压、降糖药物治疗.干预组在常规治疗的基础上给予苯溴马隆片治疗.对比研究2组治疗前、治疗后3、6、12月血尿酸、糖化血红蛋白、空腹血糖、餐后2h血糖及血糖达标率.结果 干预组患者血尿酸水平明显低于干预前及对照组,差异有统计学意义（P＜0.01）;2组患者的糖化血红蛋白、空腹血糖、餐后2h血糖、血糖达标率无明显改变.结论 降尿酸对老年高血压合并糖尿病的高尿酸血症患者的血糖无影响.

The Effects of Lowering Uric Acid Levels on the Blood Sugar of Senile Hypertension and Diabetes Mellitus Patients with High Uric Acid Levels

Objective To study the effect of lowering uric acid levels in elderly hypertensive patients with diabetes mellitus on blood sugar.Methods 100 elderly hypertensive patients with diabetes mellitus and high uric acid levels were randomly divided into control group and intervention group.The control group was given conventional diet control,antihypertensive,hypoglycemic drugs; The intervention group was given benzyl bromide Malone treatment on the basis of conventional treatment,then we compared the blood uric acid,glycosylated hemoglobin,fasting blood glucose,blood sugar 2 hours after meal and the success control rate of blood sugar between the two groups before treatment,3,6 and 12 months after treatment.Results （1） The blood uric acid level of patients in intervention group was lower than that before intervention and control group,the difference was statistically significant （P ＜ 0.01）.The glycosylated hemoglobin,fasting blood sugar,blood glucose,blood sugar 2 hours after meal and the success control rate had no obvious difference between two groups.Conclusion Lowering uric acid treatment has no effect on blood glucose in elderly hypertensive patients with diabetes mellitus.