| 肝原颗粒对实验动物的毒理学研究 |
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| 引用本文： | 谢碧桃,黄爱萍,曾斌.肝原颗粒对实验动物的毒理学研究[J].四川生理科学杂志,1994(1). |
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| 作者姓名： | 谢碧桃 黄爱萍 曾斌 |
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| 作者单位： | 泸州医学院药理教研室，泸州医学院药理教研室，泸州医学院药理教研室 泸州 646000，泸州 646000，泸州 646000 |
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| 摘 要： | 本文报告了肝原颗粒小鼠急性毒性和大鼠90天长期毒性试验。结果表明,肝原颗粒对小鼠灌胃给药的LD_(50)>252g(生药)/kg/次;大鼠90天长期毒性试验对动物一般状况、体重增长、外周血象、肝肾功能及病理组织学检查等未见明显毒性。
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| 关 键 词： | 肝原颗粒 小白鼠 大白鼠 急性毒性 长期毒性 |
STUDY ON THE TOXICOLOGY OF GANYANKELI IN EXPERIMENTAL ANIMALS |
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| Xie Bitao Huang Aiping Zen Bin.STUDY ON THE TOXICOLOGY OF GANYANKELI IN EXPERIMENTAL ANIMALS[J].Sichuan Journal of Physiological Sciences,1994(1). |
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| Authors: | Xie Bitao Huang Aiping Zen Bin |
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| Institution: | Xie Bitao Huang Aiping Zen Bin
Department of Pharmacology,Luzhou Medical College. Luzhou 646000 |
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| Abstract: | The essay reports our experiments on Ganyankeli Mouse's acute toxicity as well as rat's 90-day Long -term toxicity. The results indicated that LD50 of Ganyankeli, given by p.o. , was more than 252g (crude drug)/kg/per time, and there was no obvious long-term toxicity in the general conditions, weight increase, peripheral blood picture, functions of liver and kidney, and pathological histology in rats. |
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| Keywords: | Ganyankeli Mouse Rat Acute toxicity Long -termtoxicity |
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