胸腔积液CA125检测对结核性胸膜炎的诊断意义

目的探讨胸腔积液CA125含量检测对结核性胸膜炎的诊断意义。方法采用电化学发光法检测结核性渗出性胸膜炎胸腔积液CA125水平及腺苷脱氨酶(ADA)水平。结果结核性渗出性胸膜炎胸腔积液CA125含量水平显著升高,其阳性率为92.5%,高于胸腔积液ADA阳性率(75%)。结论胸腔积液CA125水平对结核性胸膜炎诊断敏感性高,但缺乏特异性,联合胸腔积液ADA检查可提高结核性胸膜炎的确诊率,有一定的诊断价值。

Level of the pleural effusions CA125 for the diagnosis of tuberculous pleurisy

Objective To study the value of CA125 from pleural effusions in diagnosis of tuberculous pleurisy.Methods Pleural effusions fluid CA125 and ADA of 40 clinical exudative tuberculosis pleurisy patients were measured by electrochemiluminescence assay(ECLA).Results The positive rate of CA125 in exudative tuberculosis pleurisy patients(92.5%) were higher than the rate of ADA(75%).Conclusion Pleural effusions fluid CA125 has high sensitivity but low specificity in the detection of clinical exudative tuberculosis pleurisy,the combined use of CA125 and ADA can significantly improve the chance of identifying tuberculosis pleurisy.