| 复方地蒽酚软膏的临床研究 |
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| 引用本文： | 杨宗学,陈丽,姜林芹.复方地蒽酚软膏的临床研究[J].东南国防医药,2012,14(2):117-119. |
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| 作者姓名： | 杨宗学 陈丽 姜林芹 |
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| 作者单位： | 解放军82医院149临床部药械科,江苏连云港,222042 |
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| 基金项目： | 南京军区医学科技创新资助项目（09MB118） |
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| 摘 要： | 目的评价复方地蒽酚软膏治疗寻常型银屑病的有效性和安全性。方法采用随机双盲自身对照试验,将患者皮损部位划分为两区,分别涂受试药复方地蒽酚软膏和对照药地蒽酚软膏治疗。涂药量约为0.01 g/cm2,每日涂药2次,疗程均为21 d。结果复方地蒽酚软膏临床治疗寻常型银屑病有效率为95%。不良反应主要表现为局部的刺激症状。结论该制剂治疗寻常型银屑病,疗效确切,耐受性较好,且不良反应低于对照组。
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| 关 键 词： | 复方地蒽酚软膏 银屑病 临床研究 疗效 不良反应 |
The clinical research of compound anthralin ointment |
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| YANG Zong-xue
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CHEN Li
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JIANG Lin-qin.The clinical research of compound anthralin ointment[J].Journal of Southeast China National Defence Medical Science,2012,14(2):117-119. |
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| Authors: | YANG Zong-xue CHEN Li JIANG Lin-qin |
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| Institution: | .Department of Pharmacy,149 Clinical Department of 82 Hospital of PLA,Lianyungang 222042,Jiangsu,China |
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| Abstract: | Objective Evaluation of the efficacy and safety of compound anthralin ointment treatment of psoriasis vulgaris.Methods Double-blind trials with a randomized self-control were carried out.Patients with skin lesions were divided into two groups.One group was coated with the investigational drug and another group was coated routine drug treatment.Applicator was about 0.01g/cm2 and 2 times a day.The therapy course was 21 days.Results Compound anthranol ointment in treatment of psoriasis vulgaris had an efficiency of 95%.Adverse reactions mainly local irritation.Conclusion It is effective,well tolerated using the compound anthralin ointment treatment of psoriasis vulgaris,and adverse reaction is lower than the control. |
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| Keywords: | compound anthralin ointment psoriasis clinical research effect adverse reaction |
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