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人参皂甙对慢性酒精中毒大鼠脑组织内AchE和血清中MAO活性的影响
引用本文:邹雪飞,赵海英,倪小虎.人参皂甙对慢性酒精中毒大鼠脑组织内AchE和血清中MAO活性的影响[J].黑龙江医药,2008,21(3):33-35.
作者姓名:邹雪飞  赵海英  倪小虎
作者单位:1. 哈药集团制药总厂,哈尔滨,150086
2. 哈尔滨商业大学
摘    要:用50%白酒制作慢性酒精中毒大鼠模型,分别给大鼠以高、中、低剂量的人参皂甙溶液灌胃,测定大鼠脑组织内AchE和血清中MAO的活性,来探讨人参皂甙对大鼠脑组织内AchE和血清中MAO活性的影响,实验结果表明,高剂量人参皂甙能明显抑制慢性酒精中毒大鼠血清中MAO活性,提示人参皂甙对慢性酒精中毒所致的大鼠学习记忆障碍有改善作用。

关 键 词:酒精  人参皂甙  脑组织  血清  乙酰胆碱酯酶  单胺氧化酶

The Effect of Ginsenoside on the Activity of Ache in alcohol-induced Rats' Brain Tissue and of MAO in Alcohol-induced Rats'Serum
Zou Xuefei General pharm Factory,Harbin Pharmaceutical Group Co.,Ltd..The Effect of Ginsenoside on the Activity of Ache in alcohol-induced Rats'''' Brain Tissue and of MAO in Alcohol-induced Rats''''Serum[J].Heilongjiang Medicine,2008,21(3):33-35.
Authors:Zou Xuefei General pharm Factory  Harbin Pharmaceutical Group Co  Ltd
Abstract:We made models by oral-treatment with 50% alcohol.To investigate the effect of ginsenoside on the ac- tivity of AchE in alcohol-induced rats'brain tissue and of MAO in alcohol-induced rats'serum,the high,middle and low cose groups of ginsenoside are given to the mice and we detect the activities or MAO in alcohol-induced rats serum.
Keywords:alcohol  ginsenoside  brain tissue  serum  AchE  MAO
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