宫颈炎患者支原体感染的临床研究

目的了解女性宫颈炎患者支原体感染的状况及其药敏情况,为临床治疗宫颈炎支原体感染抗生素的选择提供理论参考和依据。方法应用法国生物梅里埃公司提供的支原体IST试剂盒,对325例宫颈炎患者的宫颈分泌物进行支原体培养和药物敏感性检测。结果 325例宫颈炎患者中,291例患者支原体培养阳性,阳性率为89.5%。其中以20~30岁年龄组支原体检出率最高（94.8%）。单一解脲支原体阳性者、单一人型支原体阳性者、解脲支原体和人型支原体混合阳性者,分别占总阳性数的60.1%、23.4%和16.5%。菌落计数结果：≥104CFU/ml占71%。药敏实验结果显示：支原体对依诺沙星、氧氟沙星高度敏感（敏感率为96.6%和95.3%）,对红霉素、四环素的耐药率高（耐药率为75.3%和62.4%）。结论宫颈炎患者中支原体感染率明显上升,耐药株不断增加,喹诺酮类药可作为首选治疗药物。

Clinical study of cervicitis infected with mycoplasma

Objective To study mycoplasma infection in female cervicitis and their drug sensitivity in order to provide a theoretical reference and basis to choose antibiotics for clinical treatment of mycoplasma infection.Methods 325 cervicitis secretion suspected mycoplasma infected outpatients were detected with mycoplasma IST kits.Results 325 suspected cases were cultured and 291 were identified positive（89.5%）.Mycoplasma infection was chiefly found in female with age ranging from 16 to 55 years old（94.8%）.Among the total positive cases,60% were infected by Uu and 23.4% by Mh,16.6% cases were infected by Uu and Mh.Colony counting of 71% cases were ≥104CFU/ml.Mycoplasma was sensitive to enoxacin（96.6%）,ofloxacin（95.3%）,and resistant to erothromycin（75.3%） and tetracycline（63.4%）.Conclusion The infectious rates of myclopasma are on a big rise in female cervicitis and the resistant strains increase continuously.Quinolones can be the preferred drug.