Apparent diffusion coefficient in malignant lymphoma and carcinoma involving cavernous sinus evaluated by line scan diffusion-weighted imaging |
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Authors: | Maeda Masayuki Maier Stephan E Sakuma Hajime Ishida Masaki Takeda Kan |
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Institution: | Department of Radiology, Mie University School of Medicine, Tsu, Japan. mmaeda@clin.medic.mie-u.ac.jp |
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Abstract: | PURPOSE: To evaluate the apparent diffusion coefficient (ADC) of malignant lymphomas and carcinomas involving cavernous sinus by line scan diffusion-weighted imaging (LSDWI) and to determine the usefulness of this method for differentiating between the two tumors. MATERIALS AND METHODS: Four patients with malignant lymphomas and six patients with carcinomas were prospectively studied. LSDWI images were obtained with two different b values of 5 seconds/mm(2) and 1000 seconds/mm(2) in the coronal plane. The ADC values of the two types of tumors were calculated and compared. RESULTS: LSDWI provided diagnostic images with minimum susceptibility artifacts and enabled measurement of the ADC. The ADC value (mean +/- SD) was 0.51 +/- 0.06 x 10(-3) mm(2)/second in malignant lymphomas and 0.99 +/- 0.08 x 10(-3) mm(2)/second in carcinomas. A significant difference in ADC values was found between the two (P < 0.01). CONCLUSION: Malignant lymphomas showed significantly lower ADC value than carcinomas. ADC provides additional useful information about differentiation between these tumors. |
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Keywords: | MR imaging diffusion cavernous sinus neoplasm lymphoma |
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