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Alcohol intake and hypertension among urban and rural Japanese populations
Authors:H Ueshima  T Shimamoto  M Iida  M Konishi  M Tanigaki  M Doi  K Tsujioka  E Nagano  C Tsuda  H Ozawa
Affiliation:1. School of Food and Nutritional Sciences, University College Cork, National University of Ireland, Cork, Ireland;2. Department of Chemistry, Cork Institute of Technology (CIT), Bishopstown, Cork, Ireland;3. SRL, Biotransfer, BioInnovation Unit 327, University College Cork, Ireland;4. Department of Biological Sciences, Cork Institute of Technology, Bishopstown, Cork, Ireland;5. APC Microbiome Institute, Cork, Ireland;1. Interfaculty Initiative in Information Studies, University of Tokyo, Tokyo, Japan;2. Northern Ireland Centre for Food and Health, Ulster University, Coleraine, United Kingdom;3. Department of Social and Preventive Epidemiology, School of Public Health, University of Tokyo, Tokyo, Japan
Abstract:A significant positive relationship was found between alcohol intake and blood pressure for men 40-69 years old living in urban Osaka (492 men) and in rural Akita (395 men), Japan, surveyed from 1975 to 1977. Both mean blood pressure and the prevalence of hypertension were related to alcohol intake in a graded fashion. Stepwise multiple regression also showed that both systolic and diastolic pressure were associated with alcohol intake independent of ponderosity index, serum cholesterol, triglycerides, hemoglobin, uric acid, smoking, and age. This cross-sectional study indicates a continuous--and not a threshold--relationship between alcohol and blood pressure, with the effect of even moderate consumption, e.g. 28-55 g per day (equivalent to about 2-4 U.S. drinks per day).
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