| 慢性淋巴细胞白血病免疫表型分析 |
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| 引用本文： | 陈佳宁,王静,赵淑芳,张永宏. 慢性淋巴细胞白血病免疫表型分析[J]. 临床和实验医学杂志, 2008, 7(11): 7-8 |
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| 作者姓名： | 陈佳宁 王静 赵淑芳 张永宏 |
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| 作者单位： | 首都医科大学附属北京友谊医院检验科,北京,100050;首都医科大学附属北京友谊医院检验科,北京,100050;首都医科大学附属北京友谊医院检验科,北京,100050;首都医科大学附属北京友谊医院检验科,北京,100050 |
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| 摘 要： | 目的探讨慢性淋巴细胞白血病（CLL）细胞免疫表型。方法应用流式细胞仪，选用一系列的淋巴细胞和髓系相关抗原的单抗对42例CLL患者进行淋巴细胞表面抗原检测。结果CLL患者CD5＋／CD19＋的单克隆B细胞表达占92．9％，CD5-／CD19＋的占7．1％，CD19＋／CD20＋／HLA—DR＋的占100．0％。髓系相关抗原中CD13表达率为23．8％，CD33表达率为21．4％。结论对慢性淋巴细胞白血病患者进行免疫表型分析，对于诊断和鉴别诊断有重要意义，并为临床治疗和预后评估提供依据。
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| 关 键 词： | 慢性淋巴细胞白血病 免疫表型 |
Analysis on immunophenotypes of chronic lymphocytic leukemia |
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| CHEN Jia-ning,WANG Jing,ZHAO Shu-fang,et al.. Analysis on immunophenotypes of chronic lymphocytic leukemia[J]. Journal of Clinical and Experimental Medicine, 2008, 7(11): 7-8 |
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| Authors: | CHEN Jia-ning WANG Jing ZHAO Shu-fang et al. |
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| Affiliation: | CHEN Jia-ning,WANG Jing,ZHAO Shu-fang,et al.Beijing Friend Hospital,Capital MedicalUniversity,Beijing 100050,China. |
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| Abstract: | Objective To study the immunophenotypes of chronic lymphocytic leukemia(CLL).Methods The immunophenotypes of 42 cases of chronic lymphocytic leukemia were determined by immunocytometry.Results In CLL,the expression of CD5 /CD19 was 92.9%,CD5-/CD19 was 7.1%,CD13 was 25% and CD33 was 21%.Conclusion The immunophenotyping technique is very effective in diagnosing lymphocytic leukemia and it is helpful for the treatment and evaluation of prognosis of this disease. |
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| Keywords: | Chronic lymphocytic leukemia Immunophenotype |
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