金水宝联合黄葵治疗IgA肾病疗效观察

目的观察金水宝胶囊联合黄葵胶囊治疗IgA肾病（IgAN）患者尿蛋白、肾功能的疗效。方法：应用金水宝（虫草粉）及黄葵胶囊（黄蜀葵花提取物）联合治疗IgA肾病33例，观察12周后的相关临床指标及肾小球滤过率（GFR）变化。结果：治疗后尿视黄醇结合蛋白（RBP）、尿β2-微球蛋白（β2-M）、24小时尿蛋白定量、血CRP与治疗前比较差异均有显著性意义（P〈0．05），eGFR无显著性差异。结论：金水宝联合黄葵胶囊治疗IgA肾病安全有效，可明显减少蛋白尿、改善炎症反应保护肾功能。

The Therapeutic Efficacy of Jinshuibao Combined with Huangkui in IgAN Patients

Objective：To observe influence of Huangkui capsules combined with Jinshuibao capsules on urine protein and renal function in patients with IgAN. Methods：33 IgAN were treated with Jimhuibao plus Huangkui. Clinic index change after treatment for 12 weeks was observed,and glomerular filtration rate （GFR）was evaluated. Results：After treatment, urine protein in 24 hours,RBP, β2-M lower than before （P〈0.05 or P〈0.01 ）,while eGFR changed did not reach significance.Conclusion：Jinshniban capsules plus Huangkui capsules could obviously decrease the urine protein and inflammation reaction in patients with IgAN.