氟芬合剂对全身麻醉脊柱手术患者血流动力学的影响

目的]观察全身麻醉期间氟芬合剂对脊柱手术患者血压及心率的影响.方法]选择40例需在全身麻醉下施行脊柱手术患者,随机分为观察组和对照组,每组各为20例.观察组患者在手术开始前5 min静脉注射给予氟芬合剂6 mL,对照组给予等量生理盐水,观察手术开始后5,15,30,45 min时患者血压及心率的变化情况.结果]观察组患者手术开始后血压显著下降,心率逐渐减慢,45 min时血压及心率接近麻醉前水平,与对照组比较,血压与心率变化均有显著性差异.结论]在麻醉期间氟芬合剂可有效地降低血压,减慢心率,维持时间较长,可防止手术刺激所引起的血压升高及心率增快.

Effects of the innovar on hemodynamics during spinal surgery under general anesthesia

OBJECTIVE To observe the change of blood pressure(BP) and heart rate after the injection of innovar during general anesthesia.METHODS 40 patients underwent spinal surgery during general anesthesia were randomly divided into two groups:observation group and control group,each group included 20 cases.In observation group,each patient was intravenously injected with the innovar 6 mL 5 min before operation,patients in control group were injected with normal saline 6 mL.At skin incision, the change of BP and heart rate were monitored at 5,15,30 and 45 min,respectively.RESULTS In observation group,the patients' BP and heart rates were declined slowly.However,45 min after operation,both were closed to the level before anesthesia,and there was significant difference as compared with control group.CONCLUSION The innovar can decrease the patients' BP and heart rate efficiently for a period of time,and it can also prevent the increase of BP and heart rate caused by the stimulation of operation and maintain the patients.