| 唯地息眼凝胶剂治疗兔芥子气角膜损伤 |
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| 引用本文： | 蔡季平,赵杰,朱明学. 唯地息眼凝胶剂治疗兔芥子气角膜损伤[J]. 国际眼科杂志, 2004, 4(1): 74-76 |
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| 作者姓名： | 蔡季平 赵杰 朱明学 |
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| 作者单位： | 200003,中国上海第二军医大学附属长征医院眼科;200433,中国上海第二军医大学防化医学教研室 |
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| 摘 要： | 目的:观察唯地息眼凝胶剂对兔芥子气角膜上皮损伤的治疗作用。方法:新西兰白兔8只,用200μL/L液态芥子气致伤双眼角膜5min,左眼为治疗组,用唯地息眼凝胶剂点眼,4次/d,右眼为对照组,用2.5g/L氯霉素眼液滴眼,4次/d,分别于染毒后2,8,16,24,36,48和72h对角膜荧光素着色区拍照,计算其上皮愈合速率和上皮破损率。结果:治疗组和对照组的角膜上皮愈合速率分别为(1.15±0.19)mm2/h和(1.03±0.12)mm2/h,两者有显著差异(P<0.05),角膜上皮破损率分别为44.4%和54.2%,两者差异显著(P<0.05)。结论:唯地息眼凝胶剂能促进芥子气染毒引起的兔眼角膜损伤的上皮愈合,也能减少角膜上皮反复破损。
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| 关 键 词： | 芥子气 角膜 眼灼伤 唯地息眼凝胶剂 |
| 修稿时间： | 2003-08-24 |
Effect of carbopolymer gel on rabbit corneal wound caused by mustard gas |
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| Ji-Ping Cai,Jie Zhao,Ming-Xue Zhu. Effect of carbopolymer gel on rabbit corneal wound caused by mustard gas[J]. International Eye Science, 2004, 4(1): 74-76 |
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| Authors: | Ji-Ping Cai Jie Zhao Ming-Xue Zhu |
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| Affiliation: | Ji-Ping Cai1,Jie Zhao2,Ming-Xue Zhu21 Department of Ophthalmology,Changzheng Hospital,the Second Military Medical University,Shanghai 200003,China, 2 Department of Chemical Defense Medicine,the Second Military Medical University,Shanghai 200433,China |
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| Abstract: | |
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| Keywords: | mustard gas cornea ocular burn carbopolymer gel (Vidisic) |
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