Treatment of hyperinsulinaemic hypoglycaemia with nifedipine |
| |
| Authors: | D Eichmann M Hufnagel P Quick R Santer |
| |
| Institution: | (1) University Children's Hospital, Schwanenweg 20, D-24105 Kiel, Germany, e-mail: santer@pediatrics.uni-kiel.de, Tel.: +49-431-597-1622, Fax: +49-431-597-1831, DE |
| |
| Abstract: | We report on two children with mild persistent hyperinsulinaemic hypoglycaemia. In both, oral nifedipine treatment (0.7 and
2.0 mg/kg per day respectively) had a significant clinical effect. In one case, nifedipine monotherapy prevented hypoglycaemia;
in the second case, the dosage and the side-effects of other substances could be reduced, thus circumventing surgical therapy.
Conclusion Nifedipine treatment has a favourable effect on the clinical course of patients with mild hyperinsulinism. It represents
a valuable new substance for the treatment of this disorder.
Received: 3 March 1998 / Accepted: 3 August 1998 |
| |
| Keywords: | Nifedipine Hypoglycemia Hyperinsulinism Nesidioblastosis Persistent hyperinsulinaemic hypoglycaemia of infancy |
| 本文献已被 PubMed SpringerLink 等数据库收录！ |
|
