| 国产小剂量辛伐他汀的调脂作用 |
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| 引用本文： | 权衡,刘雪琪,权栋.国产小剂量辛伐他汀的调脂作用[J].泰山医学院学报,2001,22(1):25-26. |
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| 作者姓名： | 权衡 刘雪琪 权栋 |
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| 作者单位： | 1. 泰山医学院附属医院,山东,泰安,271000
2. 山东省医药公司,山东,济南,250013 |
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| 摘 要： | 目的 观察小剂量国产辛伐他汀（sinvastatin)的调脂作用。方法 选择原发性高胆固醇血症76例，小剂量（5mg/d）辛伐他汀治疗6周，测定血脂水平。结果 血清胆固醇、甘油三脂、低密度脂蛋白固醇、载脂蛋白B100均有下降，治疗前后对比有显著性差异；高密度脂蛋白胆固醇、载脂蛋白A1升高，治疗前后对比亦有显著性差异。结论 小剂量辛伐他汀调脂作用显著，副作用小。
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| 关 键 词： | 辛伐他汀 小剂量 调脂作用 高脂血症 治疗 |
| 文章编号： | 1004-7115(2001)01-0025-02 |
| 修稿时间： | 2000年8月2日 |
Effects of low dose domestic simvastatin on serum lipid metaboli |
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| QUAN Heng,LIU Xue-qi,QUAN Dong.Effects of low dose domestic simvastatin on serum lipid metaboli[J].Journal of Taishan Medical College,2001,22(1):25-26. |
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| Authors: | QUAN Heng LIU Xue-qi QUAN Dong |
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| Institution: | QUAN Heng1,LIU Xue-qi2,QUAN Dong2 |
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| Abstract: | Objective: To observe the effects of low dose domestic simvastatin on serum lipid metabolism. Methods: 76 patients suffering from primary cholesteremia were selected and treated with low dose (5 mg/d)simvastatin for 6 weeks. Levels of lipid were measured. Results: 6 weeks after using low dose domestic simvastatin, Serum cholesterol, triglyceride, low density lipoprotein cholesterol and lipoprotein bearer B 100 were decreased and high density lipoprotein cholesterol and lipoprotein bearer A 1 were increased significantly. Conclusion: Low dose domestic simvastatin has apparently lipid regulating effects with few side effects. |
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| Keywords: | simvastatin low dose lipids |
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