| 超微粉碎技术对圣愈颗粒溶出速率的影响 |
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| 引用本文： | 任利,张红瑞,刘雅敏,冯善涛.超微粉碎技术对圣愈颗粒溶出速率的影响[J].河南中医学院学报,2010(1). |
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| 作者姓名： | 任利 张红瑞 刘雅敏 冯善涛 |
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| 作者单位： | 福建中医学院;河南中医学院; |
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| 基金项目： | 福建省科技厅资助省属高校项目(编号:2007F5061) |
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| 摘 要： | 目的:比较圣愈超微粉颗粒与普通粉颗粒的溶出速率。方法:将圣愈汤中部分药材进行超微粉碎和普通粉碎后,分别与其它药材所得浸膏混合制为颗粒,使用药物溶出仪测定两种颗粒的溶出速率,并按威布尔分布模型进行数据处理。结果:用超微粉和普通粉药材粉末制成的圣愈颗粒的溶出速率参数T50和Td分别为49.29min、110.57min和125.52min、268.66min。结论:超微粉颗粒溶出速率明显快于普通粉颗粒。
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| 关 键 词： | 超微粉碎技术 圣愈颗粒 溶出速率 |
Effect of Ultramicro-Grinding Technology on Dissolution Velocity of Shengyu Granule |
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| Ren Li,Zhang Hongrui,Liu Yamin,Feng Shantao Fujian University of Chinese Medicine,Fuzhou,Fujian,China Henan College of Chinese Medicine,Zhengzhou,Henan,China.Effect of Ultramicro-Grinding Technology on Dissolution Velocity of Shengyu Granule[J].Journal of Henan University of Chinese Medicine,2010(1). |
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| Authors: | Ren Li Zhang Hongrui Liu Yamin Feng Shantao Fujian University of Chinese Medicine Fuzhou Fujian China Henan College of Chinese Medicine Zhengzhou Henan China |
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| Institution: | Ren Li1,Zhang Hongrui2,Liu Yamin2,Feng Shantao1 Fujian University of Chinese Medicine,Fuzhou,Fujian,China 350000 Henan College of Chinese Medicine,Zhengzhou,Henan,China 450008 |
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| Abstract: | Objective:To contrast the dissolution velocity difference between Shengyu ultramicro-powder granule and common grinding powder granule.Methods:After parts of the herb in Shengyu decoction were grinded into ultramicro-powder and common grinding powder,mix respectively with extract derived from other herbs and made into Shengyu ultramicro-granule and Shengyu common granule.The dissolution velocities of these two kinds granule were measured by Drug Dissolution Tester and data processing were made according to ... |
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| Keywords: | Ultramicro-grinding technology Shengyu granule dissolution velocity |
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