Relation of sleep state to hypoxemic episodes in ventilated extremely-low-birth-weight infants

OBJECTIVE: To determine whether hypoxemic episodes in ventilated extremely-low-birth-weight infants correlate with specific behavioral states.Study design: Three-hour video-electroencephalography-polysomnography was performed on 13 ventilated extremely-low-birth-weight infants with mean postconceptional age of 28.3 weeks. The electroencephalogram was scored for discontinuity. Rapid eye movements, body, head, and limb movements were scored from synchronized video. Sleep states were defined from electroencephalography, rapid eye movements, and movement criteria. Nonparametric statistics were used to test for differences in the proportion of time hypoxemic (oxygen saturation