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SARS病房工作的医护人员血清中特异抗体测定分析
引用本文:冯珍如,徐国宾,刘平,闫存玲,李海霞,王广发,王贵强,徐小元.SARS病房工作的医护人员血清中特异抗体测定分析[J].中国实验诊断学,2003,7(6):469-471.
作者姓名:冯珍如  徐国宾  刘平  闫存玲  李海霞  王广发  王贵强  徐小元
作者单位:1. 北京大学第一医院检验科,北京,100034
2. 北京大学第一医院呼吸科,北京,100034
3. 北京大学第一医院感染疾病科,北京,100034
摘    要:目的 检测密切接触SARS患者的医护人员血清中SARS病毒IgM及IgG抗体的水平,对SARS病毒有无隐性感染作初步调查。方法 分别用酶联免疫吸附法和间接免疫荧光法(IIFA)检测200例正常人,200例在SARS病房工作1个月的医护人员血清中SARS病毒IgM及IgG抗体的水平。结果 正常人及医护人员血清中未检测到SARS病毒IgM及IgG抗体。结论 不同于普通的流行性传染性疾病,SARS病毒可能不具有隐性感染性。

关 键 词:SARS病房  医护人员  血清  特异抗体  测定  非典型肺炎
文章编号:1007-4287(2003)06-0469-03
修稿时间:2003年12月2日

Detection on serum specific antibody of physicians and nurses worked in SARS wards
FENG Zhen-ru,XU Guo-bing,LIU Ping,et al..Detection on serum specific antibody of physicians and nurses worked in SARS wards[J].Chinese Journal of Laboratory Diagnosis,2003,7(6):469-471.
Authors:FENG Zhen-ru  XU Guo-bing  LIU Ping  
Abstract:Objective Detection on serum specific IgM or IgG antibodies to SARS associated virus in sera of physicians and nurses worked in SARS wards for one month, and investigate the possibility of subclinical infection of the disease.Methods The serum levels of anti-SARS virus IgM or IgG antibodies of 200 normal subjects, 200 physicians and nurses worked in SARS wards for one month were measured by enzyme linked immunosorbent assay and indirect immunofluorescence assay.Results Serum anti-SARS virus IgM or IgG antibodies were not detected in normal subjects and the clinical personnel.Conclusion SARS isn't like common epidemic infectious diseases and SARS virus probably hadn't the potentiality of subclinical infection.
Keywords:SARS  Enzyme linked immunosorbent assay  Indirect immuno fluorescence assay  Antibody  
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