溶栓治疗急性脑梗死对QT离散度的影响及其临床意义

目的探讨急性脑梗死溶栓成功患者和未溶栓患者QT离散度（QTd）的变化及其临床意义。方法选取77例急性脑梗死患者分为溶栓再通A组（41例）和未溶栓B组（36例）。分析两组患者QTd和QTcd（心率校正后的QTd）的变化以及室性心律失常的发生情况。结果A组QTd及QTcd较B组显著减小,差异有统计学意义（P〈0.05）;A组发生室性心律失常较B组明显减少,差异有统计学意义（P〈0.05）。结论成功溶栓的急性脑梗死患者QTd及QTcd减小,其发生室性心律失常明显减少。

Influence of thrombolytic therapy for acute cerebral infarction on QT dispersion and its clini-cal significance

Objective To investigate the changes of QT dispersion（QTd）and its clinical signif-icance for patients with acute cerebral infarction after successful thrombolytic therapy and non-throm-bolytic ones.Methods Seventy-seven patients with acute cerebral infarction were divided into thrombolytic recanalization group （group A,41 cases）and non-thrombolysis group （group B,36 cases）.Between the 2 groups,the changes of QTd and QTcd（corrected QT dispersion）and the oc-currence of ventricular arrhythmia were analysed.Results Compared with group B,QTd,QTcd and the occurrence of ventricular arrhythmia in group A all decreased significantly with statistically significant differences（P〈0.05 ）.Conclusion Amongst patients with acute cerebral infarction, their QTd and QTcd both decrease and the occurrence of ventricular arrhythmia also reduces signifi-cantly after successful thrombolytic therapy.