原发性高血压患者代谢综合征发病情况及相关危险因素分析

目的：探讨原发性高血压患者代谢综合征（MS）的发生率及其相关危险因素。方法：对1136例原发性高血压患者依据中华医学会糖尿病分会关于MS的定义进行MS筛查，并对年龄、性别、高血压病程、腹围及胰岛素抵抗指数（HOMA-IR）与Ms的发生进行回归分析，统计心血管事件、脑血管事件、肾功能异常等高血压并发症发生率。结果：男性高血压患者MS发生率较女性高（P〈0．05）；在非MS高血压患者中，女性合并血脂紊乱以及合并高BMI的比率明显高于男性（P〈0．01），男性单纯高血压及合并高血糖的比率高于女性（P〈0．01）；年龄、腹围、空腹血糖、HOMA-IR是高血压患者发生MS的危险因素，而高血压病程、收缩压、舒张压、腰臀比、BMI与MS的发生无关；MS组与非MS组相比，心血管事件及脑血管事件发生的比例均较高（P〈0．05）。结论：MS在男性中发病率较高，其发生与年龄、腹围、空腹血糖、HOMA—IR等因素有关，高血压合并MS人群发生心脑血管事件的可能性较大。

Investigation on the incidence of metabolic syndrome in patients with essential hypertension

Objective:To investigate the incidence of metabolic syndrome(MS) in patients with essential hypertension(EH) and to analyze its characteristics.Methods:A cross-sectional survey was conducted in 1 136 patients with EH.The patients were divided into MS group(217) and non-MS group(919) based on whether they were complicated with MS.Results:The incidence of MS was significantly higher in males than in females(P<0.05).Age,fasting plasma glucose,HOMA-IR and abdomen circumference were significantly different betwe...