声学定量技术评价缺血性心肌病患者左心功能

目的　探讨声学定量（AQ）技术在测定缺血性心肌病(ICM)患者左心功能中的临床应用价值。方法　测量24例ICM患者和30例正常人的左室舒张末期容积(EDV)、收缩末期容积(ESV)、射血分数(EF)、峰值充盈率(PFR)、峰值排空率(PER)、峰值充盈时间(TPFR)。结果　ICM组左室EDV为(120.08±24.50)ml,ESV为(79.78±17.38)ml，明显高于正常组(P<0.001)，ICM组左室收缩功能指标EF为(33.19±8.50)%,PER为(2.59±0.63)ml/s，较正常组明显降低(P<0.001)。ICM组的左室舒张功能指标PFR为(2.62±0.52)ml/s，较正常组明显降低;TPFR为(207.63±45.76)ms，较正常组明显延长(P<0.001)。结论　AQ技术是测定ICM患者左心功能的一项简便实用的新方法。

Evaluation of left ventricular function in patients with ischemic cardiomyopathy by acoustic quantification

Objective　To evaluate the clinical application of acoustic quantification for detecting the left ventricular function in patients with ischemic cardiomyopathy (ICM).Methods　The left ventricular function was detected in 24 patients with ischemic cardiomyopathy and 30 normal subjects.Left ventricular end diastolic volume(EDV),end systolic volume (ESV),ejection fraction (EF),peak filling rate (PFR),peak ejection rate (PER),time of peak filling rate (TPFR) were measured.Results　In ICM group , EDV was (120.08±24.50)ml,ESV was (79.78±17.38)ml, EDV and ESV were markedly higher than those in normal group (P<0.001). Left ventricular systolic function indexes in ICM group: EF was (33.19±8.50)%, PER was (2.59±0.63)ml/s, EF and PER were obviously lower than those in normal group (P<0.001). Left ventricular diastolic function indexes in ICM group: PFR was (2.62±0.52)ml/s and TPFR was (207.63±45.76)ms, PFR was obviously lower than that in normal group ,TPFR was significantly longer than that in normal group (P<0.001).Conclusions　Acoustic quantification is a new, simple, and useful method for the assessment of the left ventricular function in ICM patients.