Radiation-Induced Sequelae Affecting the Continence Organ: Incidence,Pathogenesis, and Treatment |
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Authors: | Sven Petersen Johannes Jongen Cordula Petersen Marco Sailer |
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Institution: | (1) Department of Surgery, Bethesda General Hospital Hamburg Bergedorf, Glindersweg 80, 21029 Hamburg, Germany;(2) Department of Coloproctology, Park Hospital Kiel, Kiel, Germany;(3) Department of Radiation Oncology, Oncology Center, Hamburg Altona, Hamburg, Germany |
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Abstract: | Introduction Incontinence is a late complication that causes symptoms years after radiation treatment and is difficult to deal with; it
poses a particular challenge for care-providing physicians.
Review This review looks at our current knowledge of the incidence, symptoms, and treatment of fecal incontinence induced by radiation
treatment. An approximate estimation based on retrospective data suggests an incidence of fecal incontinence of up to one-third
of patients. The mechanism that causes incontinence are changes in anal resting tone, squeeze pressure, and rectal volume
or rectal compliance. The other associated aspects of incontinence include such further disorders as proctitis, colitis, and
other disturbances involving the lower digestive tract. The therapeutic options mainly comprise the treatment of associated
aspects, such as proctitis or diarrhea.
Conclusion Surgical treatment should be the absolute exception. If the creation of a stoma is being considered, a resective procedure
offering freedom from symptoms seems to be the more advantageous option.
Presented at the meeting of the Coloproctology Group in the German Society of Visceral Surgery, Berlin, Germany, October 1,
2005.
Reprints are not available. |
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Keywords: | Radiotherapy Incontinence Incidence Pathogenesis Complication Treatment |
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