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Spatial correlation of action potential duration and diastolic dysfunction in transgenic and drug-induced LQT2 rabbits
Authors:Katja E. Odening,MD,Bernd A. Jung,Corinna N. Lang,Rocio Cabrera Lozoya,David Ziupa,Marius Menza,Jatin Relan,Gerlind Franke,Stefanie Perez FelizGideon Koren,MD,Manfred Zehender,Christoph Bode,Michael Brunner,Maxime Sermesant,Daniela Fö  ll
Affiliation:* Department of Cardiology and Angiology I, Heart Center Freiburg University, Freiburg, Germany; Department of Radiology, Medical Physics, University Hospital Freiburg, Freiburg, Germany; INRIA, Asclepios Research Project, Cardiac Modelling, Sophia Antipolis, France;§ Division of Cardiology, Cardiovascular Research Center, Rhode Island Hospital, Alpert Medical School of Brown University, Providence, Rhode Island
Abstract:
Keywords:  boldFont"  >APD, action potential duration     boldFont"  >APD  boldFont"  >75, action potential duration at 75% of repolarization     boldFont"  >[Ca  boldFont"  >2+  boldFont"  >]  boldFont"  >i, cytoplasmic Ca2+ concentration     boldFont"  >CC, correlation coefficient     boldFont"  >ECG, electrocardiogram     boldFont"  >EPS, electrophysiological study   ICa,L, L-type Ca2+ current     boldFont"  >I  boldFont"  >Kr, rapid delayed rectifier potassium current     boldFont"  >IV, intravenously     boldFont"  >LMC, wild-type littermate control     boldFont"  >LQT2, long QT syndrome type 2     boldFont"  >LQTS, long QT syndrome     boldFont"  >LV, left ventricle/ventricular     boldFont"  >MAP, monophasic action potential     boldFont"  >MRI, magnetic resonance imaging     boldFont"  >pVT, polymorphic ventricular tachycardia     boldFont"  >QTc, heart-rate corrected QT     boldFont"  >SD, standard deviation     boldFont"  >TTP, time-to-peak velocities     boldFont"  >Vr, radial velocities     boldFont"  >Vr_dia, diastolic peak radial velocities     boldFont"  >Vz, long-axis velocities     boldFont"  >Vz_dia, diastolic peak long-axis velocities
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