417例食管上皮细胞重度增生随访性研究

本文对食管上皮细胞重度增生（以下简称重度增生）417例未经特殊治疗而进行随访性研究结果说明：重度增生的自然转归结果为162例转归为食管癌，占38．8％；28例死于其它癌，占6．7％；169例死于其名病，占40．6％；58例为现症患者，占13．9％。对157例因食管癌死亡者进行了癌变时间研究说明以1~5年为多，占56．1％，其平均癌变时间为3年6月。58例重度增生现症患者进行了食管细胞学拉网复查结果说明：33例为食管正常，占56．9％；16例为轻变增生，占27．6％；1例为食管癌，占1．7％；失访8例，占13．8％。国内外类似此大量的重度增生进行随访性研究的报道极少。

A Follow-up Study of 417 Cases of Severe Esophageal Epithelial Cell Hyperplasia

Four hundred and seveteen cases of sever esophageal epithelial cell hyperplasia without speifictreatment were studied by means of follow-up. The results indicaed that the final results of the naturalcourse of the severe esophageal epithelial cell hyperplasia were esophageal cancer (38. 8%, 162/417),death of other diseases(40. 6%, 169/417), death of other cancers (6. 7%,28/417)and ekisting patientswith edageal epthelial cell hyperlasia(13. 9%, 58/417). 58 existing current patients with esophagealepithelial cell hyperplasia were investigated by cytopathology, the results were as follws: 33 cases werewith normal esophageal epithelia(56. 9% ), 16 with slight esophageal epithelial hyerplasia(27. 6% ). Iwith esophageal carcinoma (1 .7% ) and 8 missed the follow-up (13.8% ) .Such a large scaled follow-upstrdy of the sever esophageal epithelial cell hyperplasis has not been seen at home and abroad.