血液灌流联合连续性血液净化治疗急性重症胰腺炎的临床研究

目的探讨血液灌流联合连续性血液净化治疗急性重症胰腺炎的临床效果及应用价值。方法将我院治疗的80例急性重症胰腺炎患者分为观察组和对照组,对照组给予西医常规治疗,观察组在对照组治疗的基础上采取血液灌流联合连续性血液净化治疗,记录两组治疗情况。结果观察组心率、平均动脉压、血常规指标以及炎症因子改善均优于对照组,观察组患者病死率低于对照组,住院时间短于对照组,差异有统计学意义(P<0.01)。结论血液灌流联合连续性血液净化治疗急性重症胰腺炎效果可靠,能够明显降低体内炎症因子浓度,降低病死率且不增加并发症和治疗费用,值得在临床上大力推广使用。

Blood perfusion combined with continuous blood purification in the treatment of severe acute pancreatitis

Objective To explore the clinical significance and value of blood perfusion combined continu-ous blood purification therapy for severe acute pancreatitis. Methods Eighty hospitalized patients with se-vere acute pancreatitis were chosen in this study and were randomly assigned to an observation group and a con-trol group,the control group was given traditional western medicine treatment,and the observation group re-ceived the same traditional western medicine treatment as the control group plus blood perfusion combined with continuous blood purification therapy.The treatment course of the two groups was recorded. Results The observation group had better improvement in heart rate,mean arterial pressure,blood routine index and in-flammatory factor than the control group,the observation group had less fatality rate and shorter hospital du-ration than the control group,group paired comparison yielded statistically significant differences （P〈0.01）. Conclusion The results of blood perfusion combined continuous blood purification therapy for severe acute pancreatitis are reliable,and can significantly reduce body inflammation factor concentration,reduce fatality rate and does not increase complications and treatment costs,so it is worthwhile of clinical recommendation.