HLA alleles and haplotypes in the Turkish population: relatedness to Kurds, Armenians and other Mediterraneans |
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Authors: | Arnaiz-Villena A Karin M Bendikuze N Gomez-Casado E Moscoso J Silvera C Oguz F S Sarper Diler A De Pacho A Allende L Guillen J Martinez Laso J |
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Institution: | Department of Immunology and Molecular Biology, H. 12 de Octubre, Universidad Complutense, Madrid, Spain. |
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Abstract: | Turkish and Kurdish HLA profiles are studied for the first time. The comparative study of their allele frequencies, characteristic haplotypes, genetic distances with other Mediterraneans is complemented by neighbor-joining dendrograms and correspondence analyses. Turks, Kurds, Armenians, Iranians, Jews, Lebanese and other (Eastern and Western) Mediterranean groups seem to share a common ancestry: the older "Mediterranean" substratum. No sign of the postulated Indo-European (Aryan) invasion (1200 B.C.) is detected by our genetic analysis. It is concluded that this invasion, if occurred, had a relatively few invaders in comparison to the already settled populations, i.e. Anatolian Hittite and Hurrian groups (older than 2000 B.C.). These may have given rise to present-day Kurdish, Armenian and Turkish populations. |
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Keywords: | HLA Turks Kurds Armenians Jews Cretans Iberians Lebanese Egyptians Greeks Berbers Algerians Iranians |
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