老年迟发性癫Xian发作的病因、临床表现及脑电图特征分析

目的：探讨老年迟发性癫Xian发作的病因、临床特点及脑电图特征。方法：对98例老年迟发性癫Xian发作患者的病因、临床发作类型及治疗结果进行统计分析。结果：73例有明确病因,分别为脑血管病45例,脑肿瘤16例,脑外伤5例,脑萎缩5例,血液病2例;临床发作为部分性发作68例（单纯部分性发作44例,复杂部分性发作24例）,全面性发作26例,不能归类的发作4例;脑电图正常21例,异常77例,异常脑电图主要表现为低至中幅慢波增多,呈弥漫性或局限性分布,77例异常脑电图中9例出现癫Xian样放电,临床疗效：完全控制44例（45％）,部分控制24例（25％）,无效10例（10％）,死亡20例（20％）。结论：老年迟发性癫Xian大部分病因明确。临床以部分性发作为主,脑电图以慢波活动为背景,癫Xian样放电阳性率低,临床完全控制率低。

Analysis of cause of disease, clinical manifestation and EEG features in old patients with late on-set epilepsy

Objective: To explore the cause of disease, clinical manifestations and EEG features Methods: Stastical analysis of cause of disease,clinical seizure types and therapeutic effect were done in 98 patients with late on- set epileptic seizures. Results: The cause of disease was determined in 73 patients,including 45 patients with cerebral vascular disease, 16 patients with brain tumor, 5 ones with brain trauma, 5 brain atrophy and 2 patients with blood dis- eases. The types of seizures included partial seizures in 68 patients (44 patients with simple partial seizures, and 24 ones with complex partial seizures) , generalized seizures in 26 ones, and unclassified seizures in 4 patients. Normal EEGs were found in 21 patients and abnormal in 77 ones, Abnormal EEGs mainly showed increase of slow waves with low to middle amplitude,with diffuse or local distribution . Epileptiform discharges were found only in 9 of the 77 ones; The outcome of treatment were as follows: Seizure free was found in 44 patients(45%), and partly controlled seizure in 24 ones (25%), no therapeutic effect was noted in 10 patients (10%) ,and death occurred in 20 ones (20%). Conclusions: Most of old patients with late onset epilepsy might have definite cause of disease . Clinical manifestations mainly show partial seizures . Slow waves might be the background of EEGs, and EEGs showed low positive rate of epileptiform discharges. The rate of complete seizure free might be low.