双时相18F-FDG PET显像用于肿瘤良恶性鉴别诊断

目的探讨双时相^18F-FDG PET显像在肿瘤良恶性鉴别中的临床价值。方法52例单次显像难以鉴别病变性质的患者行双时相全身^18 F-FDG PET／CT显像，将显像结果与病理学检查结果对照。结果43例延迟显像SUV升高的患者中有39例经病理检查证实为恶性病变，4例为良性病变；9例延迟显像SUV降低的患者中有7例经病理检查证实为良性病变，2例为恶性病变。灵敏度为95．1％，准确性为88．5％，特异性为63．6％，阳性预测值为90．7％，阴性预测值为7／9例。结论双时相^18F—FDG PET对良恶性病变的鉴别具有较高的灵敏度和准确性。

Dual phase 18F-FDG PET imaging in the differential diagnosis of malignant and benign lesions

Objective It was realized that static PET imaging might not be accurate at fixed time point after ^18 F-FDG administration. The dual phase ^18 F-FDG PET was employed in this study in order to differentiate malignant from benign lesions. Methods Fifty-two patients with difficulty in interpreting the nature of their lesions at routine imaging underwent delayed whole body ^18F-FDG PET at 2 h post-injection. Visual inspection of PET images and SUV compared with pathological finding were used for evaluation. Results Of 43 cases with increased SUV in delay imaging, 39 were confirmed/nalignant and 4 benign. And 7 of 9 cases with decreased SUV were confirmed benign and 2 malignant. The dual phase PET imaging in this group of patients had sensitivity of 95.1%, specificity 63.6%, accuracy 88.5%, positive predictive value 90.7%, and negative predictive value 7/9. Conclusion In differentiating malignant from benign lesions, dual phase PET was more accurate than single static imaging.