| 结节性皮肤狼疮黏蛋白病3例 |
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| 引用本文： | 朱小美,徐秀莲,陈浩,孙建方. 结节性皮肤狼疮黏蛋白病3例[J]. 中国皮肤性病学杂志, 2019, 0(1): 56-59 |
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| 作者姓名： | 朱小美 徐秀莲 陈浩 孙建方 |
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| 作者单位： | 中国医学科学院北京协和医学院皮肤病研究所病理科 |
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| 基金项目： | 中国医学科学院医学与健康科技创新工程项目(CIFMS-2017-I2M-1-107) |
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| 摘 要： | 患者中2例女性,1例男性,年龄17～41岁。3例患者均表现为结节或斑块。3例患者均有相似的组织病理改变,真皮浅、深层血管及附属器周围可见淋巴细胞为主的炎症细胞灶状浸润,真皮中上层胶原纤维束之间可见黏蛋白样物质沉积;阿辛蓝染色及狼疮带实验阳性。3例均诊断为结节性皮肤狼疮黏蛋白病,且例1符合系统性红斑狼疮诊断。3例患者均对糖皮质激素及抗疟药治疗反应较好。
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| 关 键 词： | 结节性皮肤狼疮黏蛋白病 皮肤表现 病理表现 |
Three Cases of Nodular Cutaneous Lupus Mucinosis |
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| ZHU Xiaomei,XU Xiulian,CHEN Hao,SUN Jianfang. Three Cases of Nodular Cutaneous Lupus Mucinosis[J]. The Chinese Journal of Dermatovenereology, 2019, 0(1): 56-59 |
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| Authors: | ZHU Xiaomei XU Xiulian CHEN Hao SUN Jianfang |
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| Affiliation: | (Department of Pathology,Institute of Dermatology,Chinese Academy of Medical Sciences and Peking Union Medical College,Nanjing 210042,China) |
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| Abstract: | The patients included two women and one man,aging from 17 to 41years.All the patients presented with nodules or plaques.Histological examination revealed similar changes in all the patients,lymphocyte dominated inflammatory cells infiltrating in perivascular area of superficial and deep dermis and also periadnexal area,interstitial mucin deposition in the papillary and reticular dermis.Alzian blue staining and lupus band tests presented positive.Three cases were diagnosed as nodular cutaneous lupus mucinosis and the case 1 was also diagnosed as systemic lupus erythematosus.All the patients responded well to glucocorticosteroids and antimalarial azents. |
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| Keywords: | Nodular cutaneous lupus mucinosis Skin manifestations Histopathology |
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