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克隆型脂溢性角化病4例皮肤镜及反射式共聚焦显微镜影像学特征及文献复习
引用本文:沈雪,郑亚杰,崔勇.克隆型脂溢性角化病4例皮肤镜及反射式共聚焦显微镜影像学特征及文献复习[J].中国皮肤性病学杂志,2019(8):908-912.
作者姓名:沈雪  郑亚杰  崔勇
作者单位:安徽医科大学皮肤病研究所、安徽医科大学第一附属医院皮肤性病科;中日友好医院皮肤病与性病科
基金项目:米尔斯坦亚美医学基金会项目“中国人群皮肤病数字图片资源库的建立与应用”
摘    要:目的探讨克隆型脂溢性角化病皮肤镜与反射式共聚焦显微镜(RCM)特征,提高临床医生无创诊断克隆型脂溢性角化病的水平。方法回顾性分析4例克隆型脂溢性角化病的皮肤镜及RCM特征,并结合文献讨论。结果皮肤镜下3例表现为球状结构,1例表现为黑褐色均质样结构,所有皮损边界清晰;RCM下发现表皮内高折光细胞巢。结论皮肤镜与RCM检查可能为克隆型脂溢性角化病的诊断提供参考依据。

关 键 词:克隆型脂溢性角化病  皮肤镜  反射式共聚焦显微镜

Dermoscopic and Reflectance Confocal Microscopy Findings in Four Cases of Clonal Seborrheic Keratosis and Literature Review
SHEN Xue,ZHENG Yajie,CUI Yong.Dermoscopic and Reflectance Confocal Microscopy Findings in Four Cases of Clonal Seborrheic Keratosis and Literature Review[J].The Chinese Journal of Dermatovenereology,2019(8):908-912.
Authors:SHEN Xue  ZHENG Yajie  CUI Yong
Institution:(Institute and Department of Dermatology,the First Affiliated Hospital,Anhui Medical University,Hefei 230032,China;Department of Dermatology,China-Japan Friendship Hospital,Beijing 100029,China)
Abstract:Objective To investigate the dermoscopic and reflectance confocal microscopy(RCM)features of clonal seborrheic keratosis and to improve the level of non-invasive diagnosis of clonal seborrheic keratosis.Methods The dermoscopic and RCM features of clonal seborrheic keratosis were retrospectively analyzed in four cases and the literature were reviewed.Results Three cases showed globular structure under dermascopy,and one case showed a dark-brown homogenous structure.All lesions revealed sharply demarcated borders.RCM showed visible high-refractive cell nests in the epidermis.Conclusion Dermascopy and RCM may provide a basis for the diagnosis of clonal seborrheic keratosis.
Keywords:Clonal seborrheic keratosis  Dermoscopic  Reflectance confocal microscopy
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