新疆1539例女性泌尿生殖道中两种支原体在不同年龄段的分布及药敏分析

目的分析新疆某综合医院女性泌尿生殖道中的解脲脲原体和人型支原体在不同年龄段感染者中的分布及对十二种抗生素的敏感性。方法通过使用培养、PCR及药敏检测试剂盒检测患者送检的阴道分泌物,判断两种支原体在不同年龄检测者中的分布及对抗生素的敏感性。结果 1 539例女染解脲脲原体和人型支原体阳性,其中解脲脲原体单一感染的比率最高,其次是解脲脲原体与人型支原体的混合感染,人型支原体单一感染的比率最低。不同支原体在不同年龄段患者中的感染率也有所不同,仅一种支原体感染时均在26～30岁间最高,混合感染时在31～35岁间最高。两种支原体单独或合并感染时均对美满霉素、强力霉素、四环素及交沙霉素敏感,其中解脲脲原体单独感染时还对阿奇霉素和罗红霉素敏感。结论新疆女性感染的解脲脲原体和人型支原体三种感染组合状态在不同年龄段感染者中有集中趋势,两种支原体均对美满霉素、强力霉素、四环素及交沙霉素敏感,可为临床用药提供指导。

Studies of Two Type Mycoplasma Distribution in Different Age Groups Infected Person and Drug Sensitivity Among 1539 Female in Xinjiang

Objective To analyze the distribution of Ureaplasma urealyticum(UU)and Mycoplasma hominis(MH)in female patients from different age groups in a General Hospital of Xinjiang,and their sensitivity to twelve antibiotics.Methods Culture,PCR and drug sensitivity test kits were used to detect vaginal secretions of the patients,to determine the distribution of the two kinds of mycoplasmas in women of different ages and their sensitivity to antibiotics.Results A total of 1 539 women were infected with UU and MH.The rate of UU single infection was the highest,followed by mixture infection of UU and MH,and MH infection alone.The infection rate of different mycoplasmas was different in different age groups.For only one type of Mycoplasma infection,the infection rate was the highest in those aged 26~30 years,but for mixture infection,the highest rate was found in those aged 31~35 years.UU infection alone,MH infection alone or combined infection were sensitive to minocycline,doxycyline,tetracycline and josamycin,and UU infection alone was also sensitive to azithromycin and roxithromycin.Conclusion UU and MH infection as well as their combination show concentration trend among women from different age groups in Xinjiang.Both were sensitive to minomycin,doxycycline,tetracycline and josamycin,which can provide guidance for clinical medication.