| 赤芝菌丝体活性多糖的分离、纯化及结构研究 |
| |
| 引用本文： | 赵长家,何云庆.赤芝菌丝体活性多糖的分离、纯化及结构研究[J].中药材,2002,25(4):252-254. |
| |
| 作者姓名： | 赵长家 何云庆 |
| |
| 作者单位： | 北京大学药学院,北京,100083 |
| |
| 摘 要： | 赤芝(Ganoderma lucidum)固体发酵菌丝体经水堤、乙醇沉淀得总菌丝体多糖,药理实验表明,总多糖具有明显的增强免疫和抗肿瘤活性。总多糖经DEAE-Sephadex柱层析分离、脱色、脱盐得多糖 GLMB_0。总多糖经硼酸型DEAE-Cellulose柱层析分离、脱色、脱盐得多糖GLMB_1。Sephadex柱层析法和旋光法测定了两多糖的纯度。GLMB_0为肽杂多糖,GLMB_1为杂多糖。笔者通过IR、完全酸水解、GC、Smith降解、酶解、β-消除反应、CNMR对GLMB_1、GLMB_0进行了结构研究。
|
| 关 键 词： | 赤芝 多糖 菌丝体 |
| 修稿时间： | 2001年12月4日 |
Isolation, Purification and Structural Characterization of Active Polysaccharides from the Mycelimn of Ganodemalucidum |
| |
| Zhao Changjia,He Yunqing.Isolation, Purification and Structural Characterization of Active Polysaccharides from the Mycelimn of Ganodemalucidum[J].Jorunal of Chinese Medicinal Materials,2002,25(4):252-254. |
| |
| Authors: | Zhao Changjia He Yunqing |
| |
| Institution: | School of Pharmaceutical Sciences, Peking University, 100083. |
| |
| Abstract: | The active polysaccharides from the mycelium of Ganoderma lucidum were fractioned by DEAE-Sephadex and DEAE-Cellu-lose.Through repeated isolation and purification,two polysaccharides, GLMB0 and CLMB1, were finally obtained.Their structures were characterized by chemical and spectral methods. |
| |
| Keywords: | Ganoderma lucidum Polysaccharides Mycelium |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
|
