中药银杏叶提取物在精神科的应用

本文总结了中药银杏叶提取物在精神科的临床应用,及它的作用机理。该药对轻、中度老年疾呆以及脑功能不全所致的记忆力减退、认知功能障碍、情感障碍、眩晕、头痛、耳鸣等有确切疗效。与抗精神病药物合用治疗慢性精神分裂症、抑郁症能提高疗效,减轻药物副反虚。其机理可能与该药增加大脑血流量、改善能量代谢、提高乙酰胆碱周转率、消除氧自由基等作用有关。最后文章还提出今后的研究应深入比较该药对精神分裂症阳性症状和阴性症状的不同疗效,并进一步探讨其减轻精神病药物副反应的作用机理。

Application of Extract of Ginkgo Biloba in Psychiatric Medicine

Objective:We summarize the clinical application and mechanism of extract of Ginkgo Biloba (EGb 761) in psychiatric medicine. It has curative effect to hypomenesis, cognitive disorder, affectivedisorder, vertigo, headache, tintinnitus caused by senile dementia and mental retardation. Int may enhance the curative and reduce the side effects when used with psychoactive drug to treat chronic schizophrenia. Increasing cerebral-blood flow, improving energymetabolism, clearing free radical and so on are the mechanism of those action. At last the authors suggest that the difference to positive and negative symptoms accompany with schizophrenia of this medicine and the mechanism of reducing the side effects of psychoactive drug should be studied thoroughly.