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原发性鼻腔非霍奇金淋巴瘤99mTc-MIBI显像的临床初探
引用本文:刘志军,张萍,张永学.原发性鼻腔非霍奇金淋巴瘤99mTc-MIBI显像的临床初探[J].中国临床医学影像杂志,2005,16(6):317-319.
作者姓名:刘志军  张萍  张永学
作者单位:1. 华中科技大学同济医学院附属协和医院核医学科,湖北,武汉,430022
2. 广州军区武汉总医院耳鼻喉科,湖北,武汉,430070
摘    要:目的:探讨99mTc-MIBI亲肿瘤显像在原发性鼻腔非霍奇金淋巴瘤定性诊断中的应用价值。方法:经病理活检确诊的8例鼻腔非霍奇金淋巴瘤的患者进行了头颈部99mTc-MIBI早期和延迟断层显像,通过视觉判断和半定量分析,与鼻息肉及正常对照组进行比较。结果:8例非霍奇金淋巴瘤患者99mTc-MIBI早期显像均为阳性,灵敏度100%。延迟显像阳性7例,灵敏度87.5%。早期及延迟显像对鼻腔非霍奇金淋巴瘤定性诊断的特异性为70%。淋巴瘤组肿瘤/齿龈、肿瘤/腮腺、肿瘤/头皮的摄取比值与鼻息肉组及正常对照组比较差异均有显著性(P<0.05)。结论:99mTc-MIBI显像在鼻腔非霍奇金淋巴瘤的定性诊断中有较好的应用前景。

关 键 词:lymphoma  non-Hodgkin  鼻肿瘤  放射性核素显像
文章编号:1008-1062(2005)06-0317-03
收稿时间:2004-11-4
修稿时间:2004年11月4日

Value of 99mTc-MIBI imaging in the diagnosis of non-Hodgkin's lymphoma in nasal cavity
LIU Zhi-jun,ZHANG Ping,ZHANG Yong-Xue.Value of 99mTc-MIBI imaging in the diagnosis of non-Hodgkin''''s lymphoma in nasal cavity[J].Journal of China Clinic Medical Imaging,2005,16(6):317-319.
Authors:LIU Zhi-jun  ZHANG Ping  ZHANG Yong-Xue
Institution:LIU Zhi-jun1,ZHANG Ping2,ZHANG Yong-xue1
Abstract:Objective: To explore the value of 99mTc-MIBI imaging in diagnosis of non-Hodgkin's lymphoma in nasal cavity. Method: Early and delay head and neck 99mTc-MIBI SPECT images were performed in 8 patients with non-Hodgkin's lymphoma in nasal cavity, 10 cases of nasal polyp and 10 volunteers were included in the control group. Results: Eight(100%) lymphoma patients showed positive accumulation of 99mTc-MIBI in early phase and 7(87.5%) positive in delayed phase. Specificity was 70%. Tumor/gingival mucosa, tumor/parotid, tumor/scalp were significantly higher than that of the control group(P<0.05). Conclusion: 99mTc-MIBI image is useful in diagnosing non-Hodgkin's lymphoma in nasal cavity.
Keywords:lymphoma  non-Hodgkin  nose neoplasms  radionuclide imaging
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