| 流感合剂的制备与质量标准研究 |
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| 引用本文： | 陈燕芬,容穗华,郭朝光.流感合剂的制备与质量标准研究[J].中国药房,2007,18(12):909-911. |
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| 作者姓名： | 陈燕芬 容穗华 郭朝光 |
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| 作者单位： | 广东省中医院药学部,广州市,510120 |
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| 摘 要： | 目的制备流感合剂并建立其质量控制方法。方法采用煎煮和蒸馏法制备流感合剂;以薄层色谱(TLC)法鉴别大黄和姜黄;以高效液相色谱(HPLC)法测定青蒿素的含量。结果TLC能清晰地鉴别大黄、姜黄的特征斑点;青蒿素进样量在0.42~2.10μg范围内线性关系良好(r=0.9993);加样回收率为99.84%(RSD=2.15%)。结论本制剂制备方法简便,稳定性良好。TLC法专属性强,HPLC法简便、准确,可用于流感合剂的质量控制。
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| 关 键 词： | 流感合剂 姜黄 大黄 青蒿素 薄层色谱法 高效液相色谱法 |
| 文章编号： | 1001-0408(2007)12-0909-03 |
| 收稿时间： | 09 25 2006 12:00AM |
| 修稿时间： | 11 25 2006 12:00AM |
Study on Preparation and Quality Standard of Flu Mixture |
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| CHEN Yanfen,RONG Suihua,GUO Zhaoguang.Study on Preparation and Quality Standard of Flu Mixture[J].China Pharmacy,2007,18(12):909-911. |
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| Authors: | CHEN Yanfen RONG Suihua GUO Zhaoguang |
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| Institution: | Department of Pharmacy, Guangdong Traditional Chinese Medicines College, Guangzhou 510120, China |
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| Abstract: | OBJECTIVE: To prepare Flu mixture and establish its quality standard. METHODS: The methods of decoction- boiling and distillation were adopted to prepare the flu mixture; TLC was used to identify Radix Et Rhizoma Rhei and Rhizoma Curcumae Longae, and HPLC was used to determine the content of Artemisinin. RESULTS: The spots characteristic of Radix Et Rhizoma Rhei and Rhizoma Curcumae Longae. were clearly identified with TCL. A good linearity was seen of Artemisinin in the range of 0. 42～ 2. 10μ g( r=0. 999 3) . The recovery rate was 99. 84% ( RSD=2. 15% ) . CONCLUSIONS: The preparation is simple in preparation technique and good in stability. The TLC method is highly exclusive. The HPLC method is simple, accurate, and can be used for the quality control of flu mixture. |
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| Keywords: | Flu mixture Rhizoma Curcumae Longae Radix Et Rhizoma Rhei Artemisinin TLC HPLC |
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