脉冲电磁场对断肢(指)再植影响的实验研究与临床观察

目的：通过实验研究和临床观察探讨脉冲电磁场（Ｐｕｌｓｅｄ ｅｌｅｃｔｒｏｍａｇｎｅｔｉｃ ｆｉｅｌｄｓ，ＰＥＭＦ）对断肢（指）再植成活率的影响。方法对６６只Ｗｉｓｔｅｒ大白鼠行股动、静脉端－端吻合，术后ＰＥＭＦ刺激，并作血管通畅性和光镜，扫描电镜等检查，临床对４７例断肢（指）再植病人用ＰＥＭＦ刺激断肢（指）（６６肢／指），再植后未行ＰＥＭＦ刺的另外８９例（１１２肢／指）作为对照组。结果实验组血管通

Effect of pulse electromagnetic fields stimulation on replantation

Objective To explore the effect of pulse electromagnetic fields(PEMF) stimulation on replantation of amputated extremities or digits. Methods The rats and patients were stimulated by PEMF after vessels anastomosis. Results The long term patency rate of the vessels in the stimulated group was significantly higher than that of the control one (P< 0.01). Histological study revealed that the experimental group had slighter endovascular edema, minor inflammation and faster healing of the vessels. The scanning electron microscopy showed that the endothelial cells appeared earlier and aligned themselves parallel to the vessels at the anastomotic site in PEMF- treated rats. Forty seven patients (66 limbs or digits) who were treated by electromagnetic stimulation were succeeded except one(2 digits, survival rates was 97.0%). It was significantly higher than that (survival rates was 89.9%) in 89 no PEMF-treated patients (112 limbs or digits) (P<0.01). Conclusion It is considered that electromagnetic stimulation aggravates primary healing of the vessel, and thus promotes the long term patency rate.