| A New Method of Superoxide Free Radical Determination in Ischemia and Reperfusion Injury of Rat Liver |
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| 引用本文： | 武卫国,裘法祖. A New Method of Superoxide Free Radical Determination in Ischemia and Reperfusion Injury of Rat Liver[J]. 华中科技大学学报(医学英德文版), 1995, 15(3): 151-153. DOI: 10.1007/BF02888224 |
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| 作者姓名： | 武卫国 裘法祖 |
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| 作者单位： | Department of Surgery，Tongji Hospital，Tongji Medical University，Wuhan 430030 |
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| 摘 要： | ＡＮｅｗＭｅｔｈｏｄｏｆＳｕｐｅｒｏｘｉｄｅＦｒｅｅＲａｄｉｃａｌＤｅｔｅｒｍｉｎａｔｉｏｎｉｎＩｓｃｈｅｍｉａａｎｄＲｅｐｅｒｆｕｓｉｏｎＩｎｊｕｒｙｏｆＲａｔＬｉｖｅｒＷＵＷｅｉ－ｇｕｏ（武卫国）；ＱＩＵＦａ－ｚｕ（裘法祖）（Ｄｅｐａｒｔｍｅｎｔ...
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| 收稿时间： | 1994-08-10 |
A new method of superoxide free radical determination in ischemia and reperfusion injury of rat liver |
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| Wu Wei-guo,Qiu Fa-zu. A new method of superoxide free radical determination in ischemia and reperfusion injury of rat liver[J]. Journal of Huazhong University of Science and Technology. Medical sciences, 1995, 15(3): 151-153. DOI: 10.1007/BF02888224 |
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| Authors: | Wu Wei-guo Qiu Fa-zu |
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| Affiliation: | (1) Department of Surgery, Tongji Hospital, Tongji Medical University, 430030 Wuhan |
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| Abstract: | The present study was designed to utilize the chemiluminescence(CL)method for O2- analysis in ischemia and reperfusion of the whole rat liver. The results indicated that the O2- level was lower after 30 and 60 min ischemia. After 40 min reperfusion, the level of O2- increased obviously,reaching about 8. 3-fold (30min ischemia) and 9. 0-fold (60 min ischemia) (P<0.001,P<0.01) respectively.The results also show that Chinese Traditional Medicines ligustrazine and salvia compound can scavenge O2- effectively. |
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| Keywords: | superoxide free radical chemiluminescence ischemia and reperfusion injury ligustrazine salvia compound |
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