| 唐古特青兰抗脑缺氧药理研究 |
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| 引用本文： | 海平,周生祥.唐古特青兰抗脑缺氧药理研究[J].中药材,1997,20(4):198-200. |
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| 作者姓名： | 海平 周生祥 |
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| 作者单位： | 青海省高原医学科学研究所，青海省高原医学科学研究所，青海省高原医学科学研究所，青海省高原医学科学研究所 西宁 810012，西宁 810012，西宁 810012，西宁 810012 |
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| 基金项目： | 青海省卫生厅青年科技基金 |
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| 摘 要： | 藏药唐古特青兰水提液ip给药,可显著延长断头小鼠张口动作的持续时间和结扎双侧颈动脉的存活时间,显著延长小鼠尾静脉注射空气后的大口喘气开始时间和吸气停止时间,还有一定延长利多卡因中毒小鼠存活时间的趋势。另外该药对模拟高原缺氧环境所造成的大鼠脑组织病理损伤具有一定的保护作用。提示该药具有抗动物脑缺血缺氧作用。
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| 关 键 词： | 藏药 唐古特青兰 抗脑缺氧 药理 |
Antianoxic Effects of Dracocephalum tanguticum on Brain of Mice |
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| Hai Ping,Zhou Shengxiang,Shang Hong,Zhao Guilan.Antianoxic Effects of Dracocephalum tanguticum on Brain of Mice[J].Jorunal of Chinese Medicinal Materials,1997,20(4):198-200. |
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| Authors: | Hai Ping Zhou Shengxiang Shang Hong Zhao Guilan |
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| Institution: | Qinghai High Altitude Medical Science Institute, Xining 810012. |
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| Abstract: | The aqueous extracts ip of Dracocephalum tanguticum Maxim (DtM), a Tibetan medicine, prolong significantly decapitaion-induced gasping duration in mice and the survival time of mice ligated bilateral carotid (P >0. 01). DtM prolong also the primal gasping in mice after injecting the air into the coccygeal vein (P>0. 01) and the survival time in mice poisoned by Lidocaine (P>0. 05). In addition, DtM is possessed of protecting against the pathologic lession of brain in rats under stimulating high altitude hypoxic condition. The results suggest that DtM has a antianoxic effects on mice |
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| Keywords: | Tibetan Medicine Dracocephalum tanguticum Brain Anoxia |
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