| 卡托普利对高血压患者血液自由基系统的影响 |
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| 引用本文： | 何敏,刘忠铭,姜秀珍,林国珍.卡托普利对高血压患者血液自由基系统的影响[J].高血压杂志,1995(1). |
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| 作者姓名： | 何敏 刘忠铭 姜秀珍 林国珍 |
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| 作者单位： | 白求恩医科大学第三临床医学院心内科!长春，1300212，白求恩医科大学第三临床医学院心内科!长春，1300212，长春市朝阳区人民医院内科!130021，白求恩医科大学第三临床医学院心内科!长春，1300212 |
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| 摘 要： | 观察40例高血压患者血液自由基含量、血浆LPO水平和血清SOD活力及给予卡托普利治疗后的变化。高血压患者血液自由基含量及血浆LPO水平明显高于对照组（P＜0．01，P＜0．001），血清SOD活力显著低于对照组（P＜0．001）。经卡托普利治疗后血浆LPO水平明显降低（P＜0．01）．血清SOD活力增加（P＜0．05）。提示卡托普利能使高血压患者体内脂质过氧化速率降低，抗氧化能力增强，自由基代谢紊乱状态得以改善。
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| 关 键 词： | 高血压 自由基 脂质过氧化物 超氧化物歧化酶 卡托普利 |
Effects of Captopril on the Blood Free Radical System in Essential Hypertensive Patients |
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| He Min, Liu Zhongming, Jiang Xiuzhen, Lin Guozhen.Effects of Captopril on the Blood Free Radical System in Essential Hypertensive Patients[J].Chinese Journal of Hypertension,1995(1). |
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| Authors: | He Min Liu Zhongming Jiang Xiuzhen Lin Guozhen |
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| Abstract: | The plasma contents of free radicals,lipid peroxide (LPO) level and superoxide dismutase (SOD) activity before and after using treatment captopril were investigated essential hypertensive patients. The results showed that both of free radicals and LPO level were markedly higher and SOD activity lower in hypertensive patients than those in control groups.After treatment with captopril .the LPO lowered and SOD activity elevated. These findings indicated captopril could improve the metabolic balances in free redical system. |
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| Keywords: | essential hypertension free redicals lipid peroxide superoxide dismutase captoril |
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