气相色谱法测定冠心膏中樟脑、冰片和薄荷脑含量

目的探讨冠心膏中樟脑、冰片和薄荷脑含量的测定方法。方法采用气相色谱（GC）法，色谱柱为PEG-20M弹性石英毛细管色谱柱（30m×0．53mm×1μm），检测器为FID检测器。结果樟脑的线性进样量范围为0．095～0．95μg（r=0．9997，n=5），平均回收率为99．5％，RSD为1.9％；薄荷脑的线性进样量范围为0．123～1．23μg（r=0．9996，n=5），平均回收率为98．6％，RSD为2、0％；冰片的线性进样量范围为0．202—2．02μg（r=0．9997，n=5），平均回收率为99、4％，RSD为4．4％。结论GC法简便、快速、准确、重现性好，可以用于冠心膏的质量控制。

Determination of Camphor and Menthol and Borneolum syntheticum in Guanxin Plasters by GC

Objective To developing a wethod for determine the contents of camphor, menthol and borneolum syntheticum in Guanxin Plasters. Methods GC was conducted on a HP - INNOWAX column（30 m ×0.53 mm × 1μm） and naphthalene was adopted. The determinater was FID. Results Camphor showd a good linear relationship in the range of 0.095-0.95 μg, （r = 0.999 7, n = 5）. Menthol showd a good linear relationship in the range of 0. 123 - 1.23 μg, （ r = 0. 999 6, n = 5）. Borneolum syntheticum showd a good linear relationship in the range of 0.202-2.02 μg,（r=0.9997, n=5）.The average recovery rate was 99. 5% fir canogir（RSD=1.9%）,98.6% for menthol （RSD = 2.0% ） and 99.4% for borneolum syntheticum（RSD =4.0% ）, respectively. Conclusion The method is simple, rapid, accurate and reliable. It can be used for the quality control of Guanxin Plasters.