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Interferon‐induced vitiligo in hepatitis C patients: a case series
Authors:Issam Hamadah MD  Yousef Binamer MD  Faisal M. Sanai ABIM  SBG  Ayman A. Abdo MD  FRCP  Abdulmajeed Alajlan MD
Affiliation:1. Dermatology Unit, King Faisal Specialist Hospital and Research Centre, Riyadh, Saudi Arabia;2. Hepatology Division, Department of Medicine, Riyadh Military Hospital, Riyadh, Saudi Arabia;3. Gastroenterology Unit, Department of Medicine, King Khalid University Hospital, Riyadh, Saudi Arabia;4. Department of Dermatology, King Khalid University Hospital, Riyadh, Saudi Arabia
Abstract:Background Vitiligo is an autoimmune disease characterized by depigmented patches and macules. It is associated with many autoimmune diseases, the most common of which is thyroid disease. The association between Interferon (IFN) therapy and vitiligo is rarely reported in the literature, despite its common usage in hepatitis B viral infection, hepatitis C viral infection (HCV), hematological malignancies and melanoma. Case We are reporting eight cases of vitiligo that appeared after treating HCV with IFN. Conclusion Interferon unmasks vitiligo in susceptible individuals.
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