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Early bronchiectasis in cystic fibrosis detected by surveillance CT
Authors:Naveen PILLARISETTI  Barry LINNANE  Sarath RANGANATHAN
Affiliation:1. Department of Respiratory Medicine, Royal Children's Hospital, and;2. Infection, Immunity and Environment Theme, Murdoch Childrens Research Institute, Melbourne, Victoria, Australia,;3. Our Lady's Children's Hospital, Crumlin, Dublin, Ireland, and;4. Brighton and Sussex Medical School, Brighton, UK
Abstract:There is emerging evidence that cystic fibrosis lung disease begins early in infancy. Newborn screening allows early detection and surveillance of pulmonary disease and the possibility of early intervention in this life‐shortening condition. We report two children with cystic fibrosis who underwent a comprehensive assessment from diagnosis that included measurement of lung function, limited‐slice high‐resolution CT and BAL performed annually. Early aggressive surveillance enabled significant lung disease and bronchiectasis to be detected during the first few years of life and led to a change in management, highlighting a clinical role for CT scanning during the preschool years in children with cystic fibrosis.
Keywords:bronchiectasis  cystic fibrosis  radiology and other imaging infant  CT scanning
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