| Affiliation: | 1. Department of Hepatology, Postgraduate Institute of Medical Education & Research, Chandigarh, India, and;2. Department of Gastroenterology, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India, and;3. Department of Gastroenterology, GB Pant Hospital, India,;4. Institute of Liver & Biliary Sciences, India,;5. Neuroscience Research Unit, H?pital Saint‐Luc, University of Montreal, Montreal, Quebec, Canada;6. and;7. Bombay Hospital & Medical Research Centre, India,;8. Jaslok Hospital & Research Centre, Mumbai, India, and;9. Army Hospital Research & Referral, India,;10. Department of Hepatology Lakeshore Hospital, Kochi, India, and;11. Sawai Madho Singh Medical College, Jaipur, India, and;12. Department of Gastroenterology, Inver Clyde Royal Hospital, Greenock, UK;13. Motilal Nehru Medical College, University of Allahabad, Allahabad, India;14. All India Institute of Medical Sciences, New Delhi, India, and |
| Abstract: | Hepatic encephalopathy (HE) is a major complication that develops in some form and at some stage in a majority of patients with liver cirrhosis. Overt HE occurs in approximately 30–45% of cirrhotic patients. Minimal HE (MHE), the mildest form of HE, is characterized by subtle motor and cognitive deficits and impairs health‐related quality of life. The Indian National Association for Study of the Liver (INASL) set up a Working Party on MHE in 2008 with a mandate to develop consensus guidelines on various aspects of MHE relevant to clinical practice. Questions related to the definition of MHE, its prevalence, diagnosis, clinical characteristics, pathogenesis, natural history and treatment were addressed by the members of the Working Party. |
