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Molecular diagnosis of nonaneurysmal infectious aortitis
Authors:Kanemitsu Shinji  Shimono Takatsugu  Nakamura Akiko  Yamamoto Kiyohito  Wada Hideo  Shimpo Hideto
Institution:Department of Thoracic and Cardiovascular Surgery, Mie University Graduate School of Medicine, Mie, Japan. skanemitsu70@clin.medic.mie-u.ac.jp
Abstract:We report a 79-year-old patient who presented with a fever and abdominal pain. The patient was initially thought to have a retroperitoneal fibrosis or inflammatory abdominal aortitis in a normal-sized caliber aorta. Broad-range polymerase chain reaction (PCR) and DNA sequencing revealed the presence of Enterobacter. We finally diagnosed nonaneurysmal infectious aortitis, and we performed a successful surgical resection. Establishing a diagnosis of aortic infection before formation of an aneurysm is difficult. The molecular diagnostic technique was particularly useful in specifying the microbial species and diagnosis.
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