Influence of smoking in the glutathione-S-transferase M1 deficiency--associated risk for squamous cell carcinoma of the bladder in schistosomiasis patients in Egypt. |
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Authors: | A. Lafuente M. M. Zakahary M. A. el-Aziz C. Ascaso M. J. Lafuente M. Trias P. Carretero |
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Affiliation: | Institut de Salut Pública, University of Barcelona, Spain. |
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Abstract: | In this study we show an effect of the glutathione-S-transferase M1 (GSTM1) null phenotype on the risk for squamous cell carcinoma (SCC) of the bladder among male smokers in Egypt, with an adjusted odds ratio of 4.8 (95% confidence interval: 1.06-21.77). However, no overall effect of the GSTM1 null phenotype on the risk for bladder SCC was observed. |
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